1- -2-terl.-butyl

The student will doubtless be aware of the fact that methyl, ethyl, n-propyl and tso-propyl alcohols are completely miscible with water. The solubilities of the higher alcohols decrease progressively as the carbon content increases. The solubilities of all types of alcohols with five carbon atoms or more are quite small. For the isomeric butyl alcohols the solubilities (g. per 100 g. of water at 20°) are n-butyl, 8 i o-butyl, 23 ec.-butyl, 13 terl.-butyl, completely miscible. 

Cuprous bromide, 44,12 Cuprous M-butylmercaptide, 42,22 Cuprous chloride as catalyst for 1,4 addition of Grignard reagents to <, (5-unsaturated esters, 41,63 Cyanoacetic acid, terl-butyl ester, 41,5... 

Butyl oleate, 10 492 y-Butyloxycarbonyl-L-leucine anhydride, chiral derivatizing reagent, 6 76t Butylparaben, antimicrobial used in cosmetics, 7 831t terl-Butyl peroxyacetate, 13 484 terl-Butyl peroxybenzoate, 13 486 2-sec-Butylphenol (OSBP), 2 221-222 health and safety data, 2 220t physical properties of, 2 205t o-sec-Butylphenol. See 2-sec-Butylphenol (OSBP)... 

Ethyl terl-butyl ether (ETBE), 10 548, 574, 576 12 404-405 derivation from ethanol, 10 557 Ethyltoluene, 23 329, 349 o-Ethyltoluene, 23 349 p-Ethyltoluene, 10 597 p-Ethyltoluene precursor, synthesis of, 23 351 p-Ethyltoluene synthesis, molecular sieves in, 16 846... 

Fluoroalkylations arc undesirable side-reactions of hydrogen fluoride catalyzed alkylations of alkenes.208 However, selective chain elongation can be achieved in moderate yields with ethene and its halogen derivatives. Thus, various alcohols (terl-butyl, 1,1-dimethylpropyl. benzyl) and alkenes, such as cyclohexene, have been used in fluoroalkylations with ethene derivatives in the presence of hydrogen fluoride (e.g., generation of 1 and 2, respectively).205,400... 

Alkyl nitrites can also be used in anhydrous media and, for example, 4-hydroxyben-zenediazonium tetrafluoroborate is isolated in 89% yield after diazotization with isopcntyl nitrite, hydrogen fluoride and boron trifluoride in ethanol/diethyl ether.96 Diazotization can also be performed in dichloromethane or ethers (diethyl ether, tetrahydrofuran, 1,2-dimethoxyethane) with terl-butyl nitrite and boron trifluoride-diethyl ether complex which generates nitrosyl fluoride in situ.229 Excess boron trifluoride is used to trap water and tert-butyl alcohol, so that the reaction can be considered as being performed under complete anhydrous conditions. Yields are higher in dichloromethane, but 1,2-dimethoxyethane is preferred for less soluble amines. This procedure has been successfully applied to the synthesis of mono-and difluorobenzo[c]phcnanthrenes.230... 

Bis-[trifluoromethyl]-4-terl.-butyl-2-trichloromethyl- EI4b, 280 (R2C-N-CO- Ar + CljC-CHO)... 

Tetra-0-(terl.-butyl-dimethyl-silyl)- E14a/3, 645 f. (S-Ar - F)... 

Palmer and Lossing (73) obtained analogous results with isobutane. Thus for iso-CiHio, the relative primary yields of terl-butyl to isobutyl radicals were found to be in the ratio, 7 1. However, when the tertiary hydrogen atom in the molecule was replaced by deuterium this ratio dropped to about 1 2. 

Butadiene monoxide, 31, 3 Butane, 1,4-dhodo-, 30, 33 1,4-dinitro-, 34, 37 2-Butanone, 3-acetamido-, 33,1 terl-Butyl acetate, 34, 28 tt-BuTYLACETYI.ENE, 30, IS... 

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