Temgesic buprenorphine

Dogs are anaesthetized with a combination of Rompun (xylazine hydrochloride, 1 ml/10 kg, i.v.) and Ketavet (ketamine hydrochloride, 0.7 ml/10 kg, i.v.) after premedication with Temgesic (Buprenorphin, 0.2mg/kg i.m.) and ventilated with 66% N2O and 33 % O2 and 1 % Isofluorane. All procedures are performed under aseptic conditions using sterilized equipment. 

BUPRENORPHINE (Also known as Temgesic and Sub-utex.) New substances that have proven to reduce cravings associated with heroin withdrawal. May also be helpful in treating cocaine addiction. 

Buprenorphine (Temgesic, Subutex) is a new medication that has been shown to be even more effective in blocking the effects of heroin than methadone. Recent preclinical studies have shown that buprenorphine may also significantly reduce cravings associated with cocaine addiction. 

Temgesic Sublingual Tablets (Buprenorphine hydrochloride). Schering-Plough Ltd. UK Summary of product characteristics, April 2004. 

Abrahamsson J, Niemand D, Olsson A, Tbrnebrandt K. [Buprenorphine (Temgesic) as a peroperative analgesic. A multicenter study]. Anoest/iesist 1983 32(2) 75-79. 

One example is the fluoroimmunoassay for the routine detection of buprenorphine in urine samples of persons suspected of Temgesic abuse. Buprenorphine antibody is labelled with pseudobuprenor-phine, the dimer of buprenorphine. In this case, pseudobuprenorphine has a higher affinity for the antibody than that of FITC-norbuprenorphine. Pseudobuprenorphine shows an intense blue fluorescence with maximum at 435 nm when excited at 326 nm. The minimum detectable dose of buprenorphine by the fluoroimmunoassay is calculated to be 20 ng mL-i. 

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