Tartaric acid porphyrins

The synthesis of porphyrins from dipyrrylmethenes was first developed by Fischer42 and his collaborators. Different variants of this method are available. For the preparation of centrosym-metric porphyrins 7, the self-condensation of 5-bromo-5 -methyldipyrrylmethene hydrobromides or perbromides 6 in organic acid melts like succinic acid, tartaric acid or formic acid at temperatures up to 200 °C can be used. 

Kuroda et al. have reported a porphyrin-based molecular trench (Figure 74) with highly complementary binding sites for tartaric acid dialkyl esters showing association constants as high as 10 M [100]. 

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