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Targeting Cell Membrane Proteins Ligand-Gated Ion Channels

5 TARGETING CELL MEMBRANE PROTEINS LIGAND-GATED ION CHANNELS [Pg.432]

There are two main families of ligand-gated ion channel proteins that act as ionotropic receptors. One family includes the nicotinic acetylcholine receptor, the GABA-A receptor, the glycine receptor, and a class of serotonin receptor. The other family comprises various types of ionotropic glutamate receptors. Since these various ligand gated ion channels are activated by neurotransmitters, the medicinal chemistry of these proteins is presented in detail in chapter 4. [Pg.432]




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Cell membranes proteins

Cell targeting

Channels protein

Gate, membrane

Gated channels

Gated ion channels

Ion channel gates

Ion channel ligands

Ion gate

Ion gate membrane

Ion membranes

Ligand gating

Ligand-gated channels

Ligand-gated ion channels

Ligand-target

Membrane channels

Protein target

Protein targeting

Protein targeting proteins)

Protein-ligand

Proteins targeted

Target Cell

Target ion

Targets membrane

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