Target similarity

Ammonium Nitrate Plants - In ammonium nitrate plants, wet scrubbers can be considered for prill towers and the granulation plant. Particulate emissions of 0.5 kg/t of product for the prill tower and 0.25 kg/t of product for granulation should be the target. Similar loads for ammonia are appropriate. Other effluents that originate in a nitrogenous fertilizer complex include boiler blowdown, water treatment plant backwash, and cooling tower blowdown from the ammonia and nitric acid plants. 

One or more lead molecules may be used as a focusing target. Similarity metrics include Daylight fingerprint Tanimoto similarity. The penalty score for each compound in the library is defined as the distance between it and the most similar lead molecule. The penalty score for the library is the average of the individual compound penalty scores. QSAR predictions and docking scores can also be used in this term. 

The antibody-dependent lysis of tumor cells by PMNs exhibited some of the characteristics of damage mediated by products of the burst in the presence of tumor cells there was increased consumption of O2, increased formation of O and activation of the hexose monosphosphate shunt However, although a reduction in the concentration of O2 in the medium inhibited lysis neither catalase nor superoxide dismutase inhibited. The lack of effect on these enzymes was attributed to their inability to interpose themselves between the plasma membranes of the PMN and its target. Similar conclusions were reached by Clark, and Klebanoff whose data incriminated the products of the burst by the reduced killing of tumor cells by PMNs from patients with chronic granulomatous disease. Myeloperoxidase, however, appeared not to he required since neither azide or cyanide inhibited and killing by PMNs from patients with inherited deficiency of myeloperoxidase was normal. 

Active systems add an additional dimension to the imaging system because of their ability to resolve the depth of the imaging target. Similar to lateral resolution, two objects at two different ranges can be distinguished if their received phase variations differ by at least 2tt radians or one cycle as the frequency is swept over a bandwidth, B. This leads to a depth resolution of... 

Figure 10.3a shows the intensities for the metallic target. Similarly, inner shell transition lines corresponding to Ka Al5+ (O-like) to Ka Al10+ (Li-like) are seen between Al Ka and He-like 1. s2 1 s 2p (Hea) lines. As the... 

Merge canonical smiles to find out where actives overlap between two targets. Similar targets will have a high overlap of circles. 

Emergent Information from Indirect Target Similarity ... 

There are two ways to produce a pure radionuclide not contaminated with any other radioactivity. An extremely pure target can be used with a reaction path which is unique. Alternatively, the radioactive products can be purified after the end of the bombardment. For example, a 10 g sample of zinc irradiated for one week with 10 n cm s yields a sample of Zn (ti 244 d) with 7.1 X 10 Bq. If, however, the zinc target is contaminated with 0.1% of copper, in addition to the zinc activity, 3.0 x 10 Bq of Cu (ti 12.7 h) is formed. In another example element 102 believed to be discovered initially in a bombardment of a target of curium by carbon ions. The observed activity, however, was later found to be due to products formed due to the small amount of lead inq)urity in the target. Similarly, in neutron activation of samarium it must be very free of europium contamination because of the larger europium reaction cross-sections. Handbooks of activation analysis oftra contain information on the formation of interfering activities from impurities. 

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