Target receptor site

However, triggering visual imagery through auditory stimulation is clearly a central process reflecting a failure of sensory channel specificity called synesthesia. The most likely common cause of all these phenomena is impaired inhibition a likely culprit is the interference with serotonin that results from LSD occupying its target receptor sites on brain neurons. 

The lock-and-key model has developed into one of the central tenets of pharmaceutical study. Knowing the precise shape of a target receptor site allows... 

This last class of CDSs is based on formation of a reversible covalent bond between the delivered entity and some part of the targeted receptor site to enhance selectivity and activity. The targetor moiety of these CDSs is expected to undergo a modification that allows transient anchoring of the active agent. This class is less well developed than the previous ones, but it may become of increasing importance with the accumulation of receptor-related information. 

Insensitive target enzyme or target receptor site 9.3.2.1 Acetylcholinesterase... 

Mattel, C., Dechraoni, M. Y, Molgo, J. et al., Neurotoxins targeting receptor site 5 of voltage-dependent sodium channels increase the nodal volume of myelinated axons, J. Neurosci. Res. 55, 666, 1999. 

In this section theoretical studies on cephalosporins are discussed that have had as their premise the available facts regarding the chemical steps that these molecules undergo when they exert their antibacterial activity. In fact, the B-lactam antibiotics are ideally suited for quantum pharmacology studies because a great deal is known about their biochemical mode of action and the target receptor sites. The mode of action is discussed in detail elsewhere in these volumes. Research on the interaction of p-lactams with bacterial cell walls is an area not lacking frequent comprehensive reviews of the many impressive advances (see, e.g.. 

Most drugs, such as the analgesic aspirin and the decongestant ephediine, are weak organic acids or bases. In the body they switch between the ionized and neutral forms, depending on pH. This abihty is cmcial to their potency The neutral form diffuses more readily across nonpolar cell membranes to get to the target receptor site, but its ionized counterpart is more soluble in the aqueous blood plasma for distribution throughout the body. 

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