Tapering effect

The structure of this drug allowed for near immediate results due to fast acting Testosterone Acetate and Propionate. Additionally, the slow tapering effect caused by... 

A common strategy for treating chronic opiate addiction iavolves the substitution of methadone which can either be provided as maintenance therapy or tapered until abstinence is achieved. Naltrexone and buprenorphine [52485-79-7] have also been used ia this manner. The a2 adrenergic agonist clonidine [4205-90-7] provides some rehef from the symptoms of opiate withdrawal, probably the result of its mimicking the inhibitory effect of opiates on the activity of locus coerukus neurons. 

The rotor is squirrel cage with short-circuited copper rings at the ends. Here also, to vary the starting characteristics of the motor, the skin effect is used by providing deep bars, flat bars, tapered bars or other types of slots (discussed in Section 2.3). 

In the tapered labyrinth (Figure 5-5), a fixed labyrinth seals against a tapered shaft. As the shaft moves axially, the clearance of the seal changes. This allows an excess seal gas flow. The resulting venturi effect actually drags the lubricating oil into the process stream. Also, since the tapered shaft seal makes it difficult to provide an effective oil slinger, the problem is compounded. 

Damage to the labyrinth requires replacement of the expander heat barrier or compressor shaft seal. A replacement design (Figure 5-6) uses a replaceable stainless-steel labyrinth mounted on the shaft. Because the seal is not tapered, axial movement of the shaft has little or no measurable effect on seal gas flowrates. Each labyrinth has an integral oil slinger incorporated into the design. Also, each rotating... 

The lift pipe design was tapered to a larger diameter at the top. This minimized the effects of erosion and catalyst attrition, and also prevented the instantaneous total collapse of circulations when the saltation concentration, or velocity, of solids is experienced (i.e. the slump veloeity-that velocity helow which particles drop out of the flowing gas stream). In a typical operation, 2 % to 4 % eoke can he deposited on the catalyst in the reactor and burned in the regenerator. Catalyst circulation is generally not sufficient to remove all the heat of eombustion. This facilitated the need for steam or pressurized water coils to be located in the regeneration zone to remove exeess heat. 

In many practical situations involving the flow of polymer melts through dies and along channels, the cross-sections are tapered. In these circumstances, tensile stresses will be set up in the fluid and their effects superimposed on the effects due to shear stresses as analysed above. Cogswell has analysed this problem for the flow of a power law fluid along coni-cylindrical and wedge channels. The flow in these sections is influenced by three factors ... 

Solution Since the flnal section of the die lips is not tapered it may be assumed that the swelling at the die exit is due to shear effects only. 

Figure 10-79. Effect of entrance tube taper on flooding velocity. (Used by permission Diehl, J. E., and C.R. Kop Company, Chemical Engineering Progress Symposium, Heat Transfer, V. 65, No. 92, 1968. American Institute of Chemical Engineers. All rights reserved.)...

The effect of the tapered inlet tube (as earlier discussed) as now determined by English is only significant at the 60° and 75° tapers, both producing about the same increase in vapor capacity. Diehl s correlation is shown in Figure 10-79. 

The waU thickness of the taper produced by drawing down the larger tube can have an effect on the profile of the finished joint (Figure 23). If this taper has a wall thickness about the same as the unworked tube it will tend to retain its profile in working, but if it is thin-walled the joint will tend to have a rounded profile. This provides a method of controlling the type of joint produced. A rounded profile can be produced by starting with a uniformly thick rounded end. 

The particle size and size distribution of adsorbents for preparative purposes are higher and wider, respectively, compared to analytical ones. In addition, the adsorbent layer is much thicker and effectively overloaded with the compoimds. These items make resolution difficult, which must even be better than for quantitative separations as discussed in Section 5.1. These facts necessitate an excellent and superior strategy to hud the best separation, i.e., the mobile phase with the best selectivity (see Chapter 4). It was also shown that plates with a thickness gradient, called Uniplate-T taper plate [5], could improve resolution in the lower-Mp range. 

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