Taenia ovis oncosphere antigen

Dadley-Moore, D.L., Lightowlers, M.W., Rothel, J.S. and Jackson, D.C. (1999b) Synthetic peptide antigens induce antibodies to Taenia ovis oncospheres. Vaccine 17, 1506-1515. 

Harrison, G.B.L., Heath, D.D., Dempster, R.P., Lawrence, S.B., Lightowlers, M.W. and Rickard, M.D. (1993) Identification of host-protective antigens of Taenia ovis oncospheres. International journal for Parasitology 23, 41-50. 

Rickard, M.D. and Adolph, A.J. (1977) Vaccination of lambs against infection with Taenia ovis using antigens collected during short-term in vitro incubation of activated T. ovis oncospheres. Parasitology 75, 183-188. 

Gauci, C.G. and Lightowlers, M.W. (2001) Alternative splicing and sequence diversity of transcripts from the oncosphere stage of Taenia solium with homology to the 45W antigen of Taenia ovis. Molecular and Biochemical Parasitology 112, 1 73-1 81. 

Gauci, C.G., Flisser, A. and Lightowlers, M.W. (1998) A Taenia solium oncosphere protein homologous to host-protective Taenia ovis and Taenia saginata 18 kDa antigens. International Journal for Parasitology 28, 757-760. 

Osborn, P.J., Heath, D.D. and Roberts, M.G. (1982) Vaccination of sheep against Taenia ovis. The response to various dose rates of antigens obtained by incubation of oncospheres in vitro. Research in Veterinary Science 32, 351-353. 

The following species of Taenia have been grown from oncospheres to active larvae with suckers T. hydatigena, T. ovis, T. pisiformis, T. serialis and E. granulosus (308, 314). The techniques of Heath Smyth (314), or modifications of them, have been used widely by other workers for the production and collection of E/S antigens of oncospheres in the preparation of potential vaccines (see Chapter 11, p. 302). Only limited success has been achieved with the culture of larval T. saginata (310, 471) and almost none with T. solium, and the in vitro culture of these important species remains a challenge. 

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