Tables of Solvents and Volatile Buffers

Solvent Formula Molecular weight (Daltons) Boiling pt. (°C) UV cutoff (nm) 

A Practical User s Guide, Second Edition, by Marvin C. McMaster Copyright 2007 by John Wiley Sons, Inc. 

Note Usually, 1-10 mM buffer concentration is recommended for LC/MS. TFA is known to quench ionization in electrospray LC/MS, leading to lower sensitivity and should be avoided. 

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In the third appendix, I have added tables of solvents and volatile buffers important for use in LC/MS. Nonvolatile buffers cause problems when you remove solvent and ionize effluent for injection into the mass spectrometer and need to be avoided when this detector has been selected. 

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