SYT/SSX fusion

Yano M, Toyooka S, Tsukuda K, et al. SYT-SSX fusion genes in synovial sarcoma of the thorax. Lung Cancer. 2004 44 391-397. 

The SYT-SSX fusion gene encodes a protein composed of the first 379 amino acids encoded by the SYT gene and the last 78 amino acids encoded by either SSXl... 

Primers for the cDNA amplification of the complete SYT-SSX fusion transcript ... 

Lasota, J., Jasinski, M. ot al. (1998) Detection of ihe SYT-SSX fusion transcripts in formaldehyde-fixed, paraffin embedded tissue a reverse transcriptase polymerase chain reaction amplification assay useful in the diagnosis of synovial sarcoma. Mod Pathol, 11, 626-633. 

Hisaoka, M., Hashimoto, H., Iwamasa, T. et al. (1998) Primary synovial sarcoma of the lung report two cases confirmed by molecular detection of SYT-SSX fusion gene transcripts. Histopathology, 34, 205-210. 

Antonescu, C.R., Kawai, A., Leug, D.H. et al. (2000) Strong association of SYT-SSX fusion type and morphologic epithelial... 

Detection of SYT-SSX fusion transcripts in Synovial sarcoma by reverse transcriptase polymerase chain reaction using archival paraffin embedded tissues. Am J Pathol, 153, 1807-1812. 

Detection of SYT-SSX fusion transcript gene in peripheral blood from a patient with Synovial sarcoma. Am J Surg Pathol, 25, 406- 10. 

Bijwaard, K.E., Fetsch, J.F., Przygodzki, R. et al. (2002) Detection of SYT-SSX fusion transcript in archival synovial sarcoma by Real-time reverse-transcriptase polymerase chain reaction. J Mol Diag, 4, 59-64. 

Lack of SYT-SSX fusion transcripts in malignant peripheral nerve sheath tumors on RT-PCR analysis on 34 archival cases. Lab Invest, 82, 609-618. 

Ishida M, Miyamoto M, Naitoh S, Tatsuela D, Hasegawa T, Nemetto T, Yokozeki H, Nishioka K, Matsukage A, OhM M, Ohta T. The SYT-SSX fusion protein down-regulates the cell proliferation regulattH- COMl in t(x 18) synovial sarcoma. Mol Cell Biol. 2007 27 134-1355. 

---