Synthetic enhancers biological computation

Keywords Bacterial enhancers Biological computation Gene regulatory networks Synthetic enhancer... 

Unlike bacterial promoters, the coupled enhancer-a promoter systems have been completely ignored by the community in the early days of synthetic biology except for one notable exception (Atkinson et al. 2003). In addition to this work, bacterial enhancers so far have been used in three additional synthetic biology works (Amit et al. 2011 Huo et al. 2006) with no real applications as of yet. In this section, 1 will explain in computational terms why this underutilization of enhancers is expected to change as we move into developing the next phase of synthetic biology applications. 

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