Synthetic biology infection treatment

Lately, specific medical treatments that avail themselves of biological or synthetic materials have been applied to support and improve wound healing. These materials may act as passive, interactive, or bioactive dressings. Passive materials include gauzes, tulles, or other traditional products aimed at wound protection, maintenance of suitable moisture, and prevention of microbial infections (Livshits, 1988 Cornelius et al., 2007 Takeoka and Saitoh, 2012). Interactive dressings are mainly biostable polymeric films or foams that can improve gas exchange and permeability at the wound interface. Bioactive dressings have the ability to deliver active biomolecules to the lesion site (Paul and Sharma, 2004). 

Although GSH can be synthesized by the cells, these days commercial supplements of GSH are widely popular. When the plasma GSH concentration is low, such as in patients with HIV infection, alcoholics, and patients with cirrhosis, increasing the availability of circulating GSH by oral administration might be of therapeutic benefit [16]. A number of synthetic antioxidants have been established on the basis of GSH in the form of biologically active food additives, radioprotectors, and drugs used for the treatment of atherosclerosis, coronary heart disease, and intoxication of the organism [17]. GSH is found naturally in many foodstuffs (Table 22.1). 

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