Synthesis via oxidation

Total Synthesis via Oxidation Reactions of Phenol Derivatives... 

Total Synthesis via Oxidative Spiroannulation Reactions of Phenol Derivatives with PI DA or PI FA... 

Figure 5.36 Carbyne synthesis via oxide abstraction A-X = CICOCO-CI, CICO-CI, CF3C0-02CCF3, BrPh3P-Br,...

Subsequent reduction also affords (5)-2-benzyloxypropanol in 89% yield. NMR assay of the (/ )- and (5)-Mosher esters indicated no racemization over the sequence. Synthesis via oxidation of (5)-benzyloxypropanol (eq 3) provides the benzyloxypropanal with <8% racemization. ... 

FEASIBILITY OF ETHYLENE SYNTHESIS VIA OXIDATIVE COUPLING OF METHANE... 

The acetyl-CoA molecules produced by fatty acid oxidation are converted via the citric acid cycle to C02 and H20 as additional NADH and FADH2 are formed. A portion of the energy released as NADH and FADH2 are oxidized by the ETC is later captured in ATP synthesis via oxidative phosphorylation. The complete oxidation of acetyl-CoA is discussed in Chapter 10. The calculation of total number of ATP that can be generated from palmitoyl is reviewed next. 

Sorensen s synthesis via oxidative cyclization of an amino-tethered phenol... 

The efficiency of the electron transfer reactions illustrated in Fig. 1 governs a semiconductor s ability to serve as a photocatalyst for a redox reaction. This efficiency is, in turn, a function of the positions of the semiconductor s conduction and valence bands (band-edge positions) relative to the redox potentials of the adsorbed substrates. For a desired electron transfer reaction to occur, the potential of the electron acceptor should be below (more positive than) the conduction band of the semiconductor, whereas the potential of the electron donor is preferred to be above (more negative than) the valence band of the semiconductor. For an efficient organic synthesis via oxidative photocatalysis, the substrates must have potentials more negative than the valence band of the semiconductor. For an efficient organic synthesis via reductive photocatalysis, it is the reverse. 

Figure 4. DALA synthesis via oxidation of a tetrahydrofuranone. (Adapted with permission from reference 21. Copyright 1998 RSC.)...

Buchwald quickly parlayed this transformation into a versatile indole synthesis via oxidation of intermediate indolines prepared using the above intramolecular Buchwald-Hartwig amination. Variations leading directly to indoles and related nitrogen-containing heterocycles quickly followed and are described below. 

The previous catalysts were adapted for the ruthenium-catalysed benzimidazoi-soquinoline synthesis via oxidative coupling of 2-arylbenzimidazoles with alkynes. Thus [RuCl2(p-cymene)]2, with 0.5-2 equiv. of Cu(0Ac)2.H20 in toluene at reflux produced a variety of benzimidazoisoquinolines. Unsymmetrical alkynes such as phenylpropionate led to the regioselective insertion with (Ph)C-C bond formation [(Eq. 91)] [180]. As an attempt to recover the catalyst, reactions were performed in PEG-400 as a solvent medium and the products were obtained in similar yields as in toluene and the catalyst could be recycled a few times [(Eq. 91)]. 

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