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Synthesis of l,2-Benzisothiazolin-3-ones and their 1,1-Dioxides

Synthesis of l,2-Benzisothiazolin-3-ones and their 1,1-Dioxides.-From 2-(Methylsulphinyl)benzamides and Thionyl Chloride. The reaction of 2-(methylsulphinyl)benzamides with thionyl chloride, a novel and convenient [Pg.145]

Synthesis from Anilines and 2-ChlorothiobenzoyI Chloride. 2,4-(02N)2C6H3-NH2, when treated with 2-CIC6H4CSCI and oxidized with H2O2, gives [Pg.146]

Synthesis of l,2-Benzisothiazolin-3-one 1,1-Dioxides from 2-Aminobenzo-nitriles and SO - 2,6-02N(Me0)C6H3CN is reduced and the 2,6-NH2(MeO)CeH3CN is treated with NaN02 followed by SO2 to give 3-amino- [Pg.146]

4-methoxy-l,2-benzisothiazole 1,1-dioxide, which underwent demethylation followed by hydrolysis to give (53).  [Pg.146]




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1.2- Benzisothiazolin-3-one 1.1-Dioxide

2,1-Benzisothiazoline 2,2-dioxides

2- one 1,1-dioxide

L,2-Benzisothiazolin-3-one

L,2-Benzisothiazolin-3-one 1,1-dioxide

Synthesis of L-738,372 and

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