Synthesis of Ionic Liquids Under Continuous Flow

Synthesis of Ionic Liquids Under Continuous Flow 

As nitration reactions are notoriously difficult to perform on a commercial scale, the main challenge for the researchers was to develop a process that was capable of generating production volumes that were in the range of tonnes per day. The authors commented that although the reaction enthalpy is moderate, it is the potential exothermic decomposition of the product 172 that represents a safety risk. Furthermore, side reactions can also arise from the oxidation of the starting material, hence careful control of the reaction conditions is paramount on a production scale. 

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