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Synthesis enzymatic protecting group techniques

Enzymatic protecting-group techniques have recently been usedb in the synthesis of phosphopeptides, in which the phenylacetanoide group is removed from the respective phenylacetyl amides by means of PGA. In the course of the ensuing enzymatic transformations only the phenylacetamide-blocking group is attacked. The peptide bonds, the C-terminal ester, and the phosphates remain intact (Scheme 6). More importantly, the reaction conditions are so mild that no trace of P-elimination is observed. ... [Pg.299]

Reidel, A. Waldmann, H. Enzymatic Protecting Group Techniques in Bioorganic Synthesis. J. Prakt. Chem. 1993, 335, 109-127. [Pg.8]

Enzymatic Protecting Group Techniques in Organic Synthesis... [Pg.775]

Machauer, R. Waldmann, H. Synthesis of lipi-dated eNOS peptides by combining enzymatic, noble metal- and acid-mediated protecting group techniques with solid phase peptide synthesis and fragment condensation in solution. Chemistry... [Pg.109]


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Enzymatic protecting group techniques

Enzymatic protection

Enzymatic techniques

Group syntheses

Protection Techniques

Synthesis protection

Synthesis techniques

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