Syncolostemon parviflorus

Structurally related compounds hypurticin (60) and synparvolide B (61) have been isolated from yet another Hyptis species, H. urticoides, and Syncolostemon parviflorus, respectively (82, 83). The structures of (60) and (61) were determined spectroscopically with the stereochemistry of (61) being derived from its biosynthetic relationship to synparvolide A (70). 

In 2009, Srihari and group reported on stereoselective total synthesis of synparvolide B and pi-synparvolide A using Noyori s ATH of ketone as a key step. Synparvo-lides (synparvolide A, synparvolide B, and synparvolide C) were isolated from the leaves of Syncolostemon parviflorus, a medicinal plant that is used as an emetic to treat loss of appetite. " Stereoselective reduction of the ketone 141 was accomplished with (5,5)-Noyori s catalyst in i-PrOH to give l,3-fl ti-isomer in 86% yield. 

Davies-Coleman MT, Rivett DEA. 5,6-Dihydro-a-pyrones Ifom Syncolostemon parviflorus. Phytochemistry 1996 41(4) 1085-1092. 

---

See also in sourсe #XX -- [ , ]

---