Swine pepsin

Two protease fractions were observed by Herriott (see G5) on free boundary electrophoresis of crystalline swine pepsin, and two proteases were separated by Merten et al. from hog gastric extracts (M4), as well as by Taylor from human gastric juice (T6). Like pepsin, both moved to the anode at pH 2.5. 

Green, M. L., and Foster, P. D. M. (1974). Comparison of the rates of proteolysis during ripening of Cheddar cheeses made with calf rennet and swine pepsin as coagulants. J. Dairy Res. 41,269-282. 

Green, M. L. 1972. Assessment of swine, bovine and chicken pepsins as rennet substitutes for Cheddar cheesemaking. J. Dairy Res. 39, 261-273. 

H16. Herriott, R. M., Kinetics of the formation of pepsin from swine pepsinogen and identification of an intermediate compound. ] Gen. Physiol. 22, 65-78 (1938). 

Les.), and Couceiro, de Almeida, and Freire (1953) have localized it histo-chemically in the electrical tissue of Electwphorus electricus L. The distribution of carbonic anhydrase in several tissues of two teleosts and its inhibition in vivo by the sulfonamides have been investigated by Maetz (1953a,b). The presence of cathepsin in the stomachs of various animals including pike and trout has been established by Buchs (1954). A new advance has also been made in the comparative study of pepsin. This enzyme, previously crystallized from salmon (Norris and Elam, 1940), halibut (Eriksen, 1943), and shark (Sprissler, 1942), has now been crystallized from three species of tuna (Norris and Mathies, 1953). These interesting researches have shown that fish pepsins differ in crystal structure, amino acid composition, and specificity from swine or bovine pepsins and show a closer relationship to one another. As pointed out by Velick and Udenfriend (1953), specificity requirements toward substrates are less exacting with extracellular enzymes. 

Pepsin. Pepsin is derived from a z3rmogen, pepsinogen, which occurs in gastric mucosa. Pepsinogen has been obtmned from various animals and crystallized from swine. The various preparations are activated by... 

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