Suture sterility

Prior to in vivo evaluation of the suture breaking strength retention, some of the sutures were subjected to radiochemical sterilization using a 5-kGy dose.i° This sterilization process has been described briefly in Chapter 1 and can be used to achieve suture sterility without compromising its breaking strength. This is contrary to what is known to occur when absorbable sutures are radiation-sterilized using the traditional dose of about 25 kCy. 

Celcon M-90 (mg) Dose rate (kGy/h) Spore strip (cfu/mL) Spore killing (log reduction) Residual CH Olpg) Suture sterility... 

Nonsterile suture Sterile suture Nonsterile suture Sterile suture Nonsterile suture Sterile suture... 

Suture Gamma dose (kGy) Residual formaldehyde ( jg) Spore- strip colony- forming count Verified suture sterility Suture properties ... 

Surgical sutures are sterile, flexible strands used to close wounds or to tie off tubular structures such as blood vessels. Made of natural or synthetic fiber and usually attached to a needle, they are available ia monofilament or multifilament forms. Sutures are classified by the United States Pharmacopeia (USP) (1) as either absorbable or nonabsorbable. The USP also categorizes sutures according to size (diameter) and Hsts certain performance requirements. Sutures are regulated by the Food and Dmg Administration (FDA) as medical devices under the Food, Dmg, and Cosmetics (FDC) Act of 1938, the Medical Device Act of 1976, and the Medical Device Reporting regulation of 1995. 

The reduction of blood loss during or after surgical procedures where suturing or hgature is either impractical or impossible can often be accomphshed by the use of sterile, absorbable haemostats. These consist of a soft pad of sohd material packed around and over the wound which can be left in situ, being absorbed by body tissues over a period of time, usually up to 6 weeks. The principal mechanism of action of these is the ability to encourage platelet fiacture because of their fibrous or rough surfaces, and to act as a... 

SUTURE ABS SURG GEN SURGERY SIZE 2-0 13" LG UNARMED STERILE 24S 6515012513744 PG 150.16 ... 

Radiation Sterilization Use of radiation to cause a plant or animal to become incapable of reproduction tire use of radiation to kill all forms of life, especially bacteria, in food and surgical sutures. 

The peritoneum and skin are closed with sutures and dressed with sterile gauze. 

The trachea and lungs are dissected free from the heart and surrounding tissue and a sterile plastic catheter is inserted into the middle portion of the trachea and secured with silk suture. 

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