Supramolecular assemblies from

Dynamic combinatorial libraries (DCLs) are continuously interconverting libraries that evenmally evolve to an equilibrium distribution [61-65]. This approach has been used successfully in the discovery of stable supramolecular assemblies from mixtures. Due to the nearly endless possible peptide sequences that can potentially be synthesised, the DCL approach is attractive for the identification of supramolecular peptide interactions. Indeed, disulfide exchange between cysteine residues has been explored for this purpose [66, 67] as has peptide-metal binding [68]. We have recently demonstrated protease-catalysed amide exchange in this context, which allows for the evolution of the self-assembled peptide structures, and will therefore allow exploration of peptide sequence space for biomaterials design. 

Harada, A. and Kataoka, K. (1999a) Chain length recognition core-shell supramolecular assembly from oppositely charged block copolymers. Science, 283, 65-67. 

P2 J. Michl, Supramolecular Assemblies from Tinkertoy Rigid-Rod Molecules in Mesomolecules From Molecules to Materials, G. D. Mendenhall, A. Greenberg, J. F. Liebman, Chapman Hall, SEARCH Series, Vol. 1, Chapt. 5, 1995, pp. 132-160. 

Supramolecular Assemblies from Tinkertoy Rigid-Rod Molecules [J. Michl, Chapt. 5, pp. 132-160]. 

Harada A, Kataoka K. On-off control of enzymatic activity synchronizing with reversible formation of supramolecular assembly from enzyme and charged block copolymer. J Am Chem Soc 1999 121 9241-9242. 

Masci, B. Gabrielli. M. Mortera. S.E. Nierlich. M. Thuery, P. Hydrogen bonded supramolecular assemblies from uranyl ion complexes of tetrahomodioxacalix[4]ar-enes with various counterions. Polyhedron 2002, 21 (11). 1125-1131. 

Berl. V. Krische, M.J. Hue, L Lehn, J.-M. Schmutz. M. Template-induced and molecular recognition directed hierarchical generation of supramolecular assemblies from molecular strands. Chem. Eur. J. 2000. 6. 1938-1946. 

Exploiting the use of multivalent interactions in the design of photoreactive supramolecular assemblies. From solution to crystal engineering... 

Self-assembly The generation of a well-defined supermolecule from a given set of components, under appropriate conditions. The process involves three stages recognition between the components appropriate orientation of the components to allow growth of the structure termination of the growth to give a finite supramolecular species. The term also applies to the formation of supramolecular assemblies from their components. 

Supramolecular Assemblies from Pillararenes (Micellar, Vesicular and Tubular Formations)... 

Scheme 4.6 Generation of self-organized organosilicas upon transcription of supramolecular assemblies from the solutions into the solid material. (According to Refs [48,5032-58].)...

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