Sulphonylureas Tobacco

Leucine, ethanol, tobacco, the salicylates, hypoglycin A and B, pent-4-enoic acid, ouabain, isoproterenol, mesoxalate, tris-(hydroxymethyl)-aminomethane (Tham or Tris), cyclopropane carboxylic acid, monoamine oxidase (MAO) inhibitors, a few derivatives of indole, tranylcypromine and some cyclic polycarbonyls such as rhodizonate and tetrahydroxyquinone may be included among these substances. Leucine stimulates insulin secretion in infants with leucine sensitivity as well as in normal adults, especially if infused in large amounts or if the p cells have been primed by the previous administration of a sulphonylurea. 

---