Substrate Concentration of Folding Catalysis

In the initial demonstration of an effect of PPI on protein folding, 1.6 fiM PPI (1200 X/ml) was required for a sevenfold acceleration of the folding of 2 juM immunoglobulin light chains (Lang et ai, 1987). From 

Catahsis of Prolyl Isomerization in Unfolded Form of RCM-RNase Tl  

Catalysis of RNase Tl Folding by PPI Variation of Concentration of RNase Tl  

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