SUBJECTS thujone

Use of oak moss as a food additive in the United States is subject to a limitation that the finished food or beverage is thujone-free (CFR 2011). Dietary ingredients for use in dietary supplements, however, are specifically excluded from the federal food additive definition. (U.S.C. 2010). 

Although sage oil contains more thujone than absinthium oil, it has not been reported to be toxic (see absinthium). Two recent studies, however, reported that the oil may be hepato-toxic at high concentrations. Dalmation sage oil has been reported to be nonirritating and nonsensitizing to human skin when tested in a diluted form. When applied undiluted, it produced one irritation reaction in 20 subjects and was moderately irritating to rabbits. ... 

Regulatory Status. GRAS (sage, 182.10 and 182.20 Spanish sage, 182.20) no thujone limit for sage oil is specified (see absinthium). Subject of a positive German therapeutic monograph allowed for internal use in dyspeptic complaints, and as diaphoretic internally for inflamed oral mucous membranes. ... 

Regulatory Status. Has been approved for use in alcoholic beverages only finished beverage must be thujone-free ( 172.510). Yarrow oil normally contains little or no thujone, whereas sage oil contains normally about 50% thujone (see sage). The herb is the subject of a... 

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