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Subependymal giant cell astrocytoma

Much research has also been conducted on everolimus and other mTOR inhibitors for use in a number of cancers. The PDA has recently approved everolimus for organ rejection prophylaxis on April 22, 2010. A Phase II trial reports it is effective in the treatment of subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis. In Oct 2010, the PDA approved its use in SEGA unsuitable for surgery. As of Oct 2010 Phase III trials are under way in breast cancer, gastric cancer, hepatocellular carcinoma, pancreatic neuroendocrine tumors (NET), and lymphoma. ... [Pg.45]

Koenig MK, Butler U, Northrup H. (2008) Regression of subependymal giant cell astrocytoma with rapamy-cin in tuberous sclerosis complex. J Child Neurol 23 (10), 1238-1239. [Pg.229]

Giant cell astrocytoma Giant astrocytes with thick fibrils large round/oval nuclei GFAP (S) Lateral ventricle subependymal... [Pg.834]

See other pages where Subependymal giant cell astrocytoma is mentioned: [Pg.116]    [Pg.840]    [Pg.841]    [Pg.186]    [Pg.116]    [Pg.840]    [Pg.841]    [Pg.186]    [Pg.840]   


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