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Subclinical disease, therapy

LT4 is indicated for patients with overt hypothyroidism.22 However, the need for treatment is controversial in patients with mild or subclinical disease (TSH less than 10 milli-units/L). There are no large clinical trials that show an outcome benefit with treating these patients, and the therapeutic decision must be individualized.1,23 Many patients with subclinical hypothyroidism do, in fact, have subtle symptoms that improve with LT4 replacement. If the patient s serum cholesterol is elevated,24 or if serum anti-TPOAbs are present, many clinicians recommend LT4 therapy. [Pg.674]

Ascorbic acid, a water-soluble vitamin (1(X) to 250 mg p.o. daily), is indicated in the treatment of frank and subclinical scurvy in extensive bums, delayed fracture or wound healing, postoperative wound healing severe febrile or chronic disease states and in prevention of ascorbic acid deficiency in those with poor nutritional habits or increased requirements. In addition, ascorbic acid has been used for potentiation of meth-enamine in urine acidification and as an adjunctive therapy in the treatment of idiopathic methemoglobinemia. [Pg.90]

Overt thyroid disease is not observed at a rate that differs from controls or the normal population. However, patients receiving therapy should be under the care of a physician who monitors their thyroid status periodically, as subclinical hypothyroidism is a concern. For over three decades the Institute of Medicine (lOM), an operating agency of the Untied States National Academy of... [Pg.807]

A complete discussion of viral pathogenesis is beyond the scope of this chapter. In general, however, the symptoms of a viral infection may be considered to arise from the response to viral replication and cell injury in the host. These responses range from asymptomatic or subclinical to severe clinical manifestations, and they may be either local or systemic. Understanding the biochemical events that produce viral diseases can aid in the design of effective and specific therapies. Not surprisingly, viral pathogenesis occurs in distinct steps 1) viral entry into the host and primary viral replication, 2) viral spread, 3) cellular injury and host immune response, 4) viral clearance or establishment of persistent... [Pg.1856]


See other pages where Subclinical disease, therapy is mentioned: [Pg.1964]    [Pg.345]    [Pg.677]    [Pg.682]    [Pg.608]    [Pg.225]    [Pg.305]    [Pg.711]    [Pg.539]    [Pg.707]    [Pg.106]    [Pg.57]    [Pg.262]    [Pg.453]    [Pg.2376]    [Pg.75]    [Pg.789]    [Pg.807]    [Pg.892]    [Pg.78]    [Pg.364]    [Pg.411]    [Pg.97]    [Pg.299]   
See also in sourсe #XX -- [ Pg.1964 ]




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Disease therapy

Subclinical

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