2- styryl quinoxaline

Chloro-3-phenylethynylquinoxaline (91) with dimethylamine gave 2-dimethyl-amino-3-phenylethynylquinoxaline (90) (H2O, reflux, 4h 58%), but with neat ethanolamine, it gave 2-(2-hydroxyethylamino)-3-[p-(2-hydroxyethyla-mino)styryl]quinoxaline (92) (20°C, 8 h 91% note addition of the primary... 

Styryl-2(l//)-quinoxalinone (29) underwent a one-pot thiation and cyclization to give 2-phenylthieno[2,3-/7]quinoxaline (30) (P2S5, pyridine, reflux, 10 h 55%). ... 

Methylquinoxalines are converted into the corresponding carboxylic acids by condensation with an aromatic aldehyde and oxidation of the resulting styryl derivative with potassium permanganate. Quinoxaline-2-carboxylic acids are also conveniently prepared by oxidation of the readily available D-arabinotetrahydroxybutylquinoxalines with sodium peroxide in water or in a heterogeneous benzene-water system. ... 

Katkar SS, Mobile PH, Gadekar LS, Arbad BR, Lande MK (2010) ZnO-beta zeolite mediated simple and efficient method for the one-pot synthesis of quinoxaline derivatives at room temperature. Cent Eur J Chem 8(2) 320-325. doi 10.2478/sll532-009-0151-7 Katoh A, Yoshida T, Ohkanda J (2000) Synthesis of quinoxaline derivatives bearing the styryl and phenylethynyl groups and application to a fluorescence derivatization reagent. Heterocycles 52 (2) 911-920. doi 10.3987/COM-99-S61... 

Synthesis and applications in asymmetric allylic alkylation. Arkivoc xiv 103-109 Sonawane ND, Rangnekar DW (2002) Synthesis and application of 2-styryl-6,7-dichlorothiazolo [4,5-h]-quinoxaline based fluorescent dyes part 3. J Heterocycl Chem 39(2) 303-308. doi 10. 1002/jhet.5570390210... 

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