Study Estrogen-Testosteron Equilibrium

Squalene monooxygenase transforms the double bond on one end of the squalene into an epoxide. Then the cyclase enzyme catalyzes the closing of the rings. 

Everything is recycled in nature. Various enzymes can catalyze the breakdown of steroids. For example, the CYP26C1 enzyme is involved in the catabolism of all trans- and 9-ci5-retinoic acids, and thus contributes to the regulation of retinoic acid levels in cells and tissues. 

It is important to have the right equilibrium between testosterone and estrogens in males and females. Estrogens promote the development of female secondary sexual characteristics, and are also involved in the thickening of the endometrium and other aspects of regulating the menstrual cycle. In males, estrogens regulate functions of the reproductive system important to the maturation of sperm and may be necessary for a healthy libido. 

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