Structures of Bacterial Glycopolymers

OPSs of P. aeruginosa 09 (6, 7) include the same pseudaminic acid derivative but with the (i )-3-hydroxybutyryl group at N-522 (Fig. 2). 

Single O-linked residues of pseudaminic acid derivatives (or its enantiomer) modify flagellin, the major structural protein of the 

Structures of pseudaminic acid-containing OPSs from other bacteria (12-16) are shown in Fig. 4. OPSs of Vibrio cholerae 0 225 (13) and Escherichia coli 013626 (14) show marked structural similarities. 

7-Di-Ar- acety 1 p s c u d aminic acid was also found in OPS of Pseudoalteromonas atlantica T929 and CPS of Sinorhizobium sp. NGR 234,13 and 7-Ar-accLyC5-/V-(3-hydroxybutanoyl)pscudaminic acid in CPS of Sinorhizobium meliloti AK631.13 The data reported on the monosaccharides in the Sinorhizobium CPS are limited, and the full structure of none of the three polysaccharides has been determined. 

OPS of P. fluorescens has the same structure 17 as that of L. pneumophila serogroup 1 strain Philadelphia l11,31 but the degree of O-acetylation is lower ( 75%).32 P. fluorescens also produces an LPS with one monomer of the O-chain attached to the core oligosaccharide32,45 (structure 21 in Fig. 6). 5-A-Acetimidoyl-7-A-acetyllegionaminic acid was also found in the 

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