Structure-based drug design three-dimensional

Greer J, Erickson JW, Baldwin, JJ, Varney MO. Application of three-dimensional structures of protein target molecules in structure-based drug design. J Med Chem 1994 37 1035-54. 

J. Greer, J. W. Erickson, J. J. Baldwin, M. D. Varney, Application of the Three Dimensional Structures of Protein Target Molecules in Structure-Based Drug Design ,./. Med. Chem. 1994, 37, 1035-1054. 

Figure 1. Overview of structure-based drug design If the three dimensional structure of the target macromolecule is known by X-ray crystallography, NMR, or even homology modeling [7], this can serve as a starting point for what has been termed direct structure-based drug design [8]. This class of problems is usually referred to as receptor-based...

Three-Dimensional Structures of Protein Target Molecules in Structure-Based Drug Design. 

Greer, J., Erickson, J.W., Baldwin, J.J., Varney, M.D., 1994. Application of the three-dimensional stmctures of protein target molecules — structure-based drug design. J. Med. Chem. 37, 1035-1054. 

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