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Structure-based drug design iterative cycles

The iterative structure-based drug design (SBDD) cycle (lead optimization)... [Pg.267]

A SBDD design should be confirmed by a later X-ray complex structure which in turn serves to initiate a cycle of iterative structural-based drug design (SBDD). SBDD starts from X-ray or NMR complex structure of ligand with protein and a design, if synthesized, validated, and confirmed by X-ray, creates a starting point for a new level of SBDD efforts. [Pg.187]

See other pages where Structure-based drug design iterative cycles is mentioned: [Pg.591] [Pg.160] [Pg.209] [Pg.176] [Pg.282] [Pg.28] [Pg.25] [Pg.295] [Pg.326] [Pg.358] [Pg.295]

See also in sourсe #XX -- [ Pg.282 , Pg.463 ]

See also in sourсe #XX -- [ Pg.282 , Pg.463 ]

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Based Drug Design

Cycle design

Design Bases

Design structures

Drug design cycle)

Drug structure

Drug structure-based

ITER

Iterated

Iteration

Iteration iterator

Iterative

Iterative cycle

Structure based design

Structure designable

Structure drug design

Structure-based drug design