Structure and function, of receptors

Structure and Function of Receptor Tyrosine Kinases 287 TabeUe 8.1. Selected growth factors and growth factor receptors from mammals. 

Baldwin JM. Structure and function of receptors coupled to G proteins. Curr. Opin. Cell Biol. 1994 6 180-190. 

Attempts have been made to model G protein-coupled receptors [111 — 113] because of their similarity in the number of trans-membrane domains to bacteriorhodopsin. Such models prove to be useful for gaining further insight into the structure and function of receptors. However, their value for ligand design is limited at atomic resolution such models are far from reality. 

---