Structure and Catalysis

The review follows a similar pattern to that presented in Colloid Science, Volume 3, Chapter 6 with coverage of what the authors judge to be the most important developments between mid-1976 and mid-1980. In order to keep reportage within manageable proportions, some important areas, including reverse micelles in non-polar media and catalysis by polymers or in association complexes have been deliberately omitted. The former subject has been reviewed recently.  

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In view of the arguments presented in this chapter, as well as in previous chapters, it seems that electrostatic effects are the most important factors in enzyme catalysis. Entropic factors might also be important in some cases but cannot contribute to the increase of kcJKM. Furthermore, as much as the correlation between structure and catalysis is concerned, it seems that the complimentarity between the electrostatic potential of the enzyme and the change in charges during the reaction will remain the best correlator. Finally, even in cases where the source of the catalytic activity of a given enzyme is hard to elucidate, it is expected that the methods presented in this book will provide the crucial ability to examine different hypothesis in a reliable way. 

A review article entitled "Bulky amido ligands in rare-earth chemistry Syntheses, structures, and catalysis" has been published by Roesky. Benzamidinate ligands are briefly mentioned in this contexD The use of bulky benzamidinate ligands in organolanthanide chemistry was also briefly mentioned in a review article by Okuda et al. devoted to "Cationic alkyl complexes of the rare-earth metals S mthesis, structure, and reactivity." Particularly mentioned in this article are reactions of neutral bis(alkyl) lanthanide benzamidinates with [NMe2HPh][BPh4] which result in the formation of thermally robust ion pairs (Scheme 55). ... 

Smith, W.L. and Marnett, L.J. (1991). Prost andin endoperoxide synthase structure and catalysis. Biochem. Biophys. Acta 1083, 1-17. 

Greeley J, N0rskov JK, Mavrikakis M. 2002. Electronic structure and catalysis on metal surfaces. Ann Rev Phys Chem 53 319-348. 

Marletta, M. A., Nitric oxide synthase aspects concerning structure and catalysis, Cell 78 (1994), p. 927-930... 

Marmorstein R, Roth SY (2001) Histone acetyltransferases function, structure, and catalysis. Curr Opin Genet Dev 11 155-161... 

The instrumentation needed for solution studies of enzyme structure and catalysis at subzero temperatures is not difficult to build and operate. Detailed discussion of the technology is beyond the scope of this article, but a number of recent treatments provide all necessary information JJFink and Geeves, 1979 Douzou, 1974, 1977a,b). 

Imino Sugars as Active-Site Ligands for Structure and Catalysis Visualization 224... 

B. C. Gates, Supported metal clusters synthesis, structure, and catalysis. Chem. Rev. 95, 511-522 (1995). 

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