Structural characteristics, glycopeptides

One of the most characteristic features of FRET is its sensitive dependency on the fluorophore distance. This is advantageously used to evaluate structures and conformational changes of peptides, glycopeptides, and proteins among other molecules [164-166], The conformational change of the lipopeptide antibiotic daptomycin from an inactive linear form to a biological active cyclic form... 

An independent criterion for recognition of the asialo di-, tri, tri -, and tetra-antennary structures is found in the resonance patterns of theiV-aeetyl-proton signals of the glycopeptides and oligosaccharides. For comparison, these characteristic patterns, which may additionally be used as fingerprints for recognition of the type of branching of these complex carbohydrate chains, are also depicted in Fig. 14. 

Macrocyclic glycopeptide CSPs have a wide range of functional groups and characteristic shallow pocket conformation that enable them to interact with enantiomers through all possible intermolecular interactions. Depending on solute structure and mobile-phase conditions, ionic/electrostatic, H-bonding, and n-n interactions are probably the most dominant interactions between the solutes and CSPs, while dipole-dipole, hydrophobic, steric, and other interactions also play roles in the chiral recognition process [53-56],... 

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