Stripping voltammetry biology

Anodic stripping voltammetry (ASV) has been used extensively for the determination of heavy metals in samples of biological origin, such as lead in blood. ASV has the lowest detection limit of the commonly used electroanalytical techniques. Analyte concentrations as low as 10 M have been determined. Figure 16 illustrates ASV for the determination of Pb at a mercury electrode. The technique consists of two steps. The potential of the electrode is first held at a negative value for several minutes to concentrate some of the Pb " from the solution into the mercury electrode as Pb. The electrode process is... 

Iodine and iodine derivatives are ubiquitous in nature and a report describing the determination of iodine in environmental and biological samples has been published [197]. Electrochemical techniques are important, in particular, for inorganic iodine species in aqueous media. The direct detection of iodine by differential pulse and stripping voltammetry has been reported... 

The concentration levels of most trace metals and metalloids lie below 1000 pg P . Therefore, the classical methods of analysis do not have the required sensitivity. Among the instrumental techniques that have been extensively used for the analysis of biological materials include, atomic absorption spectrometry, plasma emission spectrometry, anodic stripping voltammetry and neutron activation analysis. 

Mader, P., Szakova, J., Curdova, E. Combination of classical dry ashing with stripping voltammetry in trace element analysis of biological materials review of literature published after 1978. Talanta 43, 521-534 (1996)... 

Zimmermann, S., Messerschmidt, J., von Bohlen, A., Sures, B. Determination of platinum, palladium and rhodium in biological samples by electrothermal atomic absorption spectrometry as compared with adsorptive cathodic stripping voltammetry and total-reflection X-ray fluorescence analysis. Anal. Chim. Acta 498, 93-104 (2003)... 

Davidson, I.E. Smyth, W.E. Cathodic stripping voltammetry of some sulfur-containing organic compounds in biological fluids. Anal. Chem. 1977, 49, 1195-1198. 

A number of methods have been described for determining the concentrations of toxic metals in biological samples.These methods include graphite furnace atomic absorption spectrometry (GF-AAS), electroanalytical techniques such as anodic stripping voltammetry (ASV), neutron activation analysis (NAA), and mass spectrometry (MS). Amongst these techniques, mass spectrometry occupies a unique role due to its potential to measure the... 

S. Yang and S. H. Wang, Determination of trace iodine in food and biological samples by cathodic stripping voltammetry, Anal. Chem. 63 (24), 2970-3... 

C. L. Newbury and G. D. Christian, Anodic Stripping Voltammetry of Biological Samples, J. Electroanal. Chem. 9, 468 (1965). 

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