Stress-induced bone remodeling

On the other hand, Fukada et al.[5] found piezoelectricity properties in bone which was stressed. There are several reports [11,20,21] which are based on evidence that bone demonstrates a piezoelectric effect. This is used to explain the concept of stress- or strain-induced bone remodelling which is often refered to as Wolfs law[3]. Thus, bone converts mechanical stress to an electrical potential that influences the activity of osteoclasts and osteoblasts[l]. It is also known that the interior structure of bone(trabecular architecture) is arranged in compressive and tensile systems corresponding to the principal stress directions[4]. The role of the voltage signals induced in bamboo and palm we found may also be similar to the piezoelectric effect in bone. 

Injury, infection, stress-induced hormones (glucocorticoids), parathyroid hormone (Sect. 10.3.1), and increased pressure on a bone all decrease osteoprotegerin (OCIF) production by osteoblasts, causing greater differentiation of osteoclasts, more bone remodeling, and more... 

It has been shown that the fluid flow-induced shear stress applied on bone cells is an important factor bone formation and remodeling [5]. Moreover, targeted remodeling that is... 

---