Streptococcus Group structure

In a study concerning the immunospecificity of the capsular polysaccharides of Streptococcus group B, type III, Jennings et al (1981) applied HC-NMR spectroscopy as a main tool for structure analysis. The native capsular polysaccharide consists of a backbone of -6)GlcNAc (l 3)Galp(l-4)Glcp(l-... 

There are solitary examples of other alditol phosphates as components of this class of polymers. Arabinitol 1-phosphate is part of the S. pneumoniae type 17F capsular polysaccharide. o-Glucitol 6-phosphate is a component of the group-specific polysaccharide from group B Streptococcus, which has a most unusual, ramified structure. In a polysaccharide from Nocardia... 

Scheme 4 Structures of the Group A Streptococcus cell-wall polysaccharide, and of branched trisaccharide (1) and hexasaccharide (2) fragments recognized by antibodies...

Skin and skin structure infections- Skin and skin structure infections, including abscesses, cellulitis, infected skin ulcers, and wound infections caused by S. aureus (including penicillinase-producing strains) Streptococcus pyogenes, group D streptococcus including . faecalis, Acinetobacter sp. including iA. calcoaceticus] Citrobactersp.] E. coli] Enterobacter cloacae, K. pneumoniae]... 

Although it has, to date, not been possible to identify any common structural feature among all the polysaccharide capsules of bacteria associated with the most pathogenic human disease, there is one common feature in many of them. The capsular polysaccharide of type III group B Streptococcus has terminal sialic acid residues in its structure,62,63 as do the groups B and C N. meningitidis and K1 E. coli.3 -34 The ability of terminal sialic acid residues to inhibit the activation of complement by way of the alternative pathway has been well docu-... 

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