Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Stratum comeum swelling

FIGURE 12.1 Penetration enhancer activity, (a) Action at intercellular lipids. Some of the ways by which penetration enhancers attack and modify the well-organized intercellular lipid domain of the stratum comeum. (b) Action at desmosomes and protein structures. Such dramatic disruption by enhancers (particularly potent solvents) as they split the stratum corneum into additional squames and individual cells would be clinically unacceptable, (c) Action within comeocytes. Swelling, further keratin denaturation and vacuolation within individual horny layer cells would not be so drastic but would usually be cosmetically challenging (see Menon and Lee [69] for further details). (Reproduced from Barry, B.W., Nat. Biotechnol. 22, 165, 2004. With permission.)... [Pg.236]

Rhein LD, CR Robbins, K Femee, and R Cantore, Surfactant structure effects on swelling of isolated human stratum comeum. Journal of the Society of Cosmetic Chemists, 37, 125-139, 1986. [Pg.177]

Stratum Comeum (SC) Beginning of swelling assodeted wilh a partial rupture of vertical Knkages... [Pg.96]

The denaturation and swelling of stratum corneum proteins by surfactants has been used for predicting the irritation potential of surfactants. Different sources of stratum comeum... [Pg.471]

Collagen/stratum Swelling of a collagen/stratum comeum sheet 7-9... [Pg.471]

Table 2 Variations in Stratum Comeum (SQ/Collagen Swelling... Table 2 Variations in Stratum Comeum (SQ/Collagen Swelling...
The method is able to predict the irritation potential of anionic surfactants or mixtures of different types of surfactant. However, as observed for stratum comeum/collagen swell-... [Pg.473]

Chain length of sodium alkyl carboxylate Human skin irritancy Positive reactions to 22.5 mM solutions (%) Rat skin irritancy Assessed score for irritancy (macroscopic and microscopic). 0.25 M solutions for 15 min, once daily for 3 days Collagen disc swelling Change in thickness, critical micelle concentration (%) Extraction of stratum comeum Increase relative to water Proteins Amino acids (%) Ion conductance of stratum comeum Rate of change of conductance (Mohm/cm /min xlO" )... [Pg.664]

See other pages where Stratum comeum swelling is mentioned: [Pg.14]    [Pg.21]    [Pg.71]    [Pg.77]    [Pg.260]    [Pg.244]    [Pg.268]    [Pg.48]    [Pg.164]    [Pg.457]    [Pg.268]    [Pg.254]    [Pg.123]    [Pg.30]    [Pg.457]    [Pg.472]   
See also in sourсe #XX -- [ Pg.446 , Pg.471 ]



SEARCH



Strata

© 2024 chempedia.info