Storage processes holding period

The survival of encapsulated RBC s was determined by Drabkins test. Approximately 71% of encapsulated cells survived for 4 days as opposed to 96% of a control sample isolated at the same time and stored in TRIS buffered saline. Although these results indicate that the process of encapsulation followed by a short storage period did not result in undue necrosis, caution must be used in any extrapolations toward the behavior of nucleated cells. Even so, these indefinitely stable and mechanically resilient coatings hold promise as an alternative to polylysine treatment for the post stabilization of calcium alginate gel prior to transplantation. 

Solution stability is a key factor in the utility of solution processes for fabrication of polymers. Due to the hold up of polymer solution in process mixers, storage tanks and process lines, it is necessary that a completely stable solution be employed. Instability, which results in phase out or precipitation of a polymer from solution, will cause contamination or blockage of the system and shut down the process. Since both the CAPE and BRAPE polyesters are not amenable to melt processing, it is extremely important to be able not only to prepare solutions but also that these solutions be stable at high concentrations for extended periods of time. 

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