Stimulator pixels

Fig. 7.1 The working and the counter electrode of one stimulating pixel in the subretinal implant of [1], the working electrode is the disk in the middle and the counter electrode is the hexagonal ting at periphery, both in dark brown, picture from [1], with permission...

The main difference of our project is the development of a retina encoder which simulates the signal processing of the different layers of the retina. The encoder transforms visual information into stimuli for the ganglion cells. The stimulation patterns should resemble the ones obtained from a non damaged retina. In detail, a high speed, pixel addressable camera with a light sensitivity of... 

Fig. 3. Time course analysis of the API promoter activity in individual cells A Luminescence images of PC12 cells expressing luciferase gene under the API promoter after EGF stimulation. Images were taken with 14 min exposure at 15 min intervals and binning with lxl of 512 x 512 pixels using a 40 x objective lens (NA 1.35). B Time course analysis of API promoter activity after EGF stimulation. Each line represents the luminescence intensity for individual cells.

Rothermel A, Wieczorek V, Liu L, Stett A, Gerhardt M, Harscher A, Kibbel S (2008) A 1600-pixel Subretinal Chip with DC-free Terminals and 2 V Supply Optimized for Long Lifetime and High Stimulation EflBciency. Solid-State Circuits Conference, 2008. ISSCC 2008. Digest of Technical Papers. IEEE International, pp. 144-602,3-7 Feb. 2008. 

---