Violence from stimulants

Hypoparathyroidism.—A. Acute.—Complete parathyroidectomy in the dog is followed by (i.) hypocalcsemia, the serum Ca level falling by 50 per cent, to about 6 mg. per 100 ml. (ii.) hyperexcitability of the peripheral nerves to electrical and mechanical stimuli, muscular twitching (iii.) tetanic spasm, due to central stimulation in the brain stem. These increase in violence, with alternate phases of exhaustion, until death results from asphyxia owing to respiratory spasm, or cardiac failure. 

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