Steroid pulse

Kamoda T, Nakahara C, Matsui A. A case of empty sella after steroid pulse therapy for nephrotic syndrome. J Rheumatol 1998 25(4) 822-3. 

Kobayashi S, Warabi H, Hashimoto H. Hypopituitarism with empty sella after steroid pulse therapy. J Rheumatol 1997 24(l) 236-8. 

OhtsukiN., KimuraS., Nezu A., and Aihara Y. (2000) [Effects of mild hypothermia and steroid pulse combination therapy on acute encephalopathy associated with influenza virus infection report of two cases]. No To Hattatsu 32, 318-322. 

A 26-year-old asthmatic woman had severe acute necrotizing eosinophilic endomyocarditis while taking pranlukast, inhaled beclomethasone, and oral theophylline (4). Oral prednisolone had been replaced by pranlukast 9 months before the event. Cardiac injury was accompanied by peripheral eosinophilia, cardiogenic shock, and pulmonary infiltrates, suggesting atypical Churg-Strauss syndrome. She recovered after intensive treatment, steroid pulse therapy, and withdrawal of pranlukast. 

Pardos-Gea J, Altisent C, Parra R, VilardeU-Tarres M, Ordi-Ros J. Acquired haemophilia A. First line treatment with calcineurin inhibitors and steroid pulses a 10-year foUow-up study. Haemophilia September 2012 18(5) 789-93. PubMed PMID 22429259. Epub 2012/03/21. eng. 

A high-dose intravenous steroid pulse is the standard treatment for uncomplicated acute rejection. A switch from CsA to Tac is the first treatment step of refractory acute rejection followed by high-dose steroids or antilymphocyte agents, total lymphoid irradiation or extracorporeal photopheresis. 

In a study of long range ET between aromatic donor (biphenyl) and acceptor molecules separated by steroid spacers [39], pulse radiolysis and electron beam techniques have been used for the injection of electrons (Closs and Miller, 1988 Closs et al., 1989 Liang et al, 1990). Here, the reaction rates (observed by changes in the absorption spectra) pass through a... 

Spectra.—Pulsed Fourier-transform n.m.r. spectroscopy of labelled steroids,... 

Frequently, the constant release of a drug from pharmaceutical dosage forms enables one to obtain a suitable pharmacological and therapeutic response. However, for therapy of certain pathologies, i.e. some heart and rheumatic diseases, or in the utilization of some drags such as contraceptive steroids and antibiotics, it would be more useful to obtain different plasma levels of the active principle at different times related to painful symptoms or circadian rhythms, etc. In these cases the desired therapeutic results can usually be obtained with frequent administration of conventional dosage forms which lead to a prompt absorption of the active principle. This kind of drag treatment is often compromised by a lack of full compliance by the patient. Until now there have been few systems that allow the release of the active principle in successive pulses at precise and well-controlled time periods [11,12]. 

Lower pulse frequencies favor FSH secretion, whereas higher pulse frequencies favor LH secretion. Gonadal steroids as well as the peptide hormones activin and inhibin have complex modulatory effects on the gonadotropin response to GnRH. 

Oshitani N, Kamata N, Ooiso R, Kawashima D, Inagawa M, Sogawa M, Iimuro M, Jinno Y, Watanabe K, Higuchi K, Matsumoto T, Arakawa T. Outpatient treatment of moderately severe active ulcerative colitis with pulsed steroid therapy and conventional steroid therapy. Dig Dis Sci 2003 4 1002-5. 

The year 1983 got off to a brisk start with the appearance of a communication by Calcaterra and co-workers, in which they reported observing very rapid thermal intra-molecular ET in radical anions of D-B-A dyads, such as 16(9) and 17(10), in which the chromophores are attached to a rigid steroid bridge (Scheme 7).90 The edge-to-edge distance between the two chromophores in these molecules is about 11 A and they are separated by nine C-C bonds. The radical anions of 16(9) and 17(9) were generated by pulse radiolysis in 2-methyltetrahydrofuran at room... 

Otto, A. M., A one minute pulse of estradiol to MCF-7 breast cancer cells changes estrogen receptor binding properties and commits cells to induce estrogenic responses. J. Steroid Biochem. Mol. Biol. 54, 39-46 (1995). 

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