Stepwise progression of resistance

The Stepwise Progression of Resistance. Resistance was first noted for insects, when Melander reported in 1914 that San Jose scale on apples in Washington State had become insensitive to lime-sulfur (33). This was greeted with some skepticism, and was followed by scattered reports, limited to insects, over the next 30 years. By 1946, resistance was documented for only 11 species (40). 

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See also in sourсe #XX -- [ , ]

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