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Staphylococcal pathogenicity islands

Yarwood JM, McCormick JK, Paustian ML, Orwin PM, Kapur V, Schlievert PM Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3. Implications forthe evolution of staphylococcal pathogenicity islands. J Biol Chem 2002 277 13138-13147. [Pg.37]

The situation in staphylococci is somewhat different. The first staphylococcal pathogenicity islands (SaPIs) identified (SaPIs 1,2, and 3) were discovered because of their carriage of the genes for toxic shock syndrome toxin-1 (TSST-1) and other superantigens. They were soon found to be highly mobile, owing to their relationship with certain phages [3]. The SaPIs are inserted at specific... [Pg.42]

Staphylococcal superant en-like (SSL) protein 7 is a 23 kDa protein that belongs to a family of 11 different SSLs that are clustered on staphylococcal pathogenicity island 2 (Sapln2). SSL7 binds to %A but also prevents formation of the MAC via specific binding to C5. SSL7 binding to C5 possibly also prevents formation of C5a which seems more important for clearance of S. aureus because its thick cell wall renders it resistant to MAC-mediated lysis. [Pg.36]

Baba T, Bae T, Schneewind O, Takeuchi F, Hiramatsu K (2008) Genome sequence of Staphylococcus aureus strain Newman and comparative analysis of staphylococcal genomes polymorphism and evolution of two major pathogenicity islands. J Bacteriol 190 300-310 Bannerman TL, Kloos WE (1991) Staphylococcus capitis subsp. ureolyticus subsp. nov. from human skin. Int J Syst Bacteriol 41 144-147... [Pg.165]


See other pages where Staphylococcal pathogenicity islands is mentioned: [Pg.161]    [Pg.183]    [Pg.43]    [Pg.45]    [Pg.51]    [Pg.53]    [Pg.161]    [Pg.183]    [Pg.43]    [Pg.45]    [Pg.51]    [Pg.53]    [Pg.140]    [Pg.145]    [Pg.162]    [Pg.42]    [Pg.82]   


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Pathogenicity islands

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