Standard Transformed Gibbs Energies Biochemical Reactants

A number of biochemical reactions involve proteins as reactants, and so it is important to be able to determine the standard transformed Gibbs energies of formation of their reactive sites at specified pH. The standard transformed Gibbs energies of formation of the active sites of ferredoxin, cytochrome c, and thioredoxin are given in tables discussed earlier in Chapter 4. 

R. A. Alberty, Effect of temperature on standard transformed Gibbs energies of formation of reactants at specified pH and ionic strength and apparent equilibrium constants of biochemical reactions, J. Phys. Chem. 105 B, 7865-7870 (2001). (Supplementary Information is available.)... 

Module[ energy, ( Calculates the standard transformed Gibbs energy of reaction in kJ mol -1 at specified pHs and ionic strengths for a biochemical reaction typed in the form atp+h2o+de= adp+pi. The names of reactants call the appropriate functions of pH and ionic strength. pHlist and is list can be lists. ) energy b Solve[eq, de] ... 

The biochemical reactants ATP, ADP, and phosphate each exist in several different ionized and metal bound forms. For example, ATP is an equilibrium mixture of the species ATP, HATP, H ATP, MgATP ", MgHATP", Mg ATP". Additional species would also have to be considered if Ca + were present. Thus, ATP has often been denoted in the literature as ZATP or as (ATP). When it is clear that one is dealing with total amounts of substances, it is not necessary to use either the Z or tot. Thus, these designations are not used in this table. In the above equation, c° = 1 mol dm" it is included to make K dimensionless. The standard transformed Gibbs energy of reaction A G ° at specified conditions of temperature T, pressure P, ionic strength 1, pH, and pMg can be calculated from 1C ... 

Values of A G ° and K can rdso be calculated for many biochemical reactions by using the table Standard Transformed Gibbs Energies of formation for Biochemical Reactants in Section 7 of this Handbook. 

Alberty RA. (1998). Calculation of standard transformed Gibbs free energies and standard transformed enthalpies of biochemical reactants. Archives of Biochemistry and Biophysics 353(1) 116-130. 

Alberty RA (1998) Calculation of Standard Transformed Gibbs Energies and Standard Transformed Enthalpies of Biochemical Reactants. Arch Biochem Biophys 353 116-130 and corresponding references... 

Standard Transformed Gibbs Energies of Formation for Biochemical Reactants.7-19... 

This table contains values of the standard transformed Gibbs energies of formation for 130 biochemical reactants. Values... 

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