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SREBP family of transcription factors

Sundqvist, A., Bengoechea-Alonso, M. T., Ye, X., Lukiyanchuk, V., Jin, J., Harper, J. W., and Ericsson, J. Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7). Cell Metab 1 (2005) 379-391. [Pg.45]

Members of a family of nuclear transcription factors called sterol regulatory element-binding proteins (SREBP) are responsible for the regulation of these cholesterol feedback mechanisms. SREBP are able to activate a number of genes encoding for proteins involved in the homeostasis of cholesterol and other lipids, including the LDL receptor gene itself. [Pg.156]

The rate of synthesis of HMG-CoA reductase messenger RNA (mRNA) is controlled by one of the family of sterol regulatory element binding proteins (SREBPs)(Fig. 34.4A). These transcription factors belong to the helix-loop-helix-... [Pg.623]

See other pages where SREBP family of transcription factors is mentioned: [Pg.106]    [Pg.578]    [Pg.10]    [Pg.277]    [Pg.282]    [Pg.106]    [Pg.578]    [Pg.10]    [Pg.277]    [Pg.282]    [Pg.223]    [Pg.446]    [Pg.10]    [Pg.177]    [Pg.184]    [Pg.206]    [Pg.282]    [Pg.440]    [Pg.186]    [Pg.884]    [Pg.887]    [Pg.111]    [Pg.182]    [Pg.208]    [Pg.228]    [Pg.557]   
See also in sourсe #XX -- [ Pg.9 ]



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