Sponges Spongia officinalis

Lenis, L., Nunez, L., Jimenez, C., and Riguera, R., Isonitenin and acetylhomoagmatine, new metabolites from the sponges Spongia officinalis and Cliona celata collected at the Galician coast (N.W. Spain), Nat. Prod. Lett., 8, 15, 1996. 

CiMiNO, G. S., S. DE Stefano, and L. Minale Oxidized Furanoterpenes from the Sponge Spongia officinalis. Experientia 30, 18 (1974). 

Migliuolo, A., Notaro, G Picdalli, V, and Sica, D. (1990) New tetrahydroxylated sterols from the marine sponge Spongia officinalis. J. Nat. Prod., 53,1414-1424. 

Cimino, G De Stefano, S Minale, L and Fattomsso, E. (1972e) Minor C-21 furanoterpenes from the sponge Spongia officinalis and Hippospongia communis. Tetrahedron, 28, ICJ-lli. 

Cimino, G De Rosa, D De Stefano, S and Minale, L. (1974b) Isoagafliolactone, a diterpene of a new structural type from the sponge Spongia officinalis. Tetrahedron, 30,645-649. 

Cimino, G., De Stefano, S., Minale, L., and Fattorusso, E. (1971) Eurospongin-1, a new C-21 furanoterpene from the sponges Spongia officinalis and Hippospongia communis. Tetrahedron, 27, 4673-4679. 

Oxidized furanoterpenes from the sponge Spongia officinalis. Experientia 30,... 

Minor C-21 furanoterpenes from the sponges Spongia officinalis and... 

Isocopalane and its tetracyclic furan derivatives, referred to as spongianes, are found in various sponges such as Spongia officinalis, and in the naked snails eating these sponges. Such compounds include (+)-isocopalene-15,16-dial, the cyclohe-miacetal (-)-spongiane-15,16-diol, the lactone (+)-l ip-hydroxy-12-spongiene-16-... 

Madaio, A., Piccialli, V., Sica, D., and Corriero, G. (1989) New polyhydroxysterols from the Dictyoceratid sponges Hippospongia communis, Spongia officinalis, Ircinia variabilis and Spongionella gracilis.]. Nat. Prod., 52, 952-961. 

Only one example of a true diterpenoid compound has so far been reported from sponges. It has been isolated from Spongia officinalis (45) from which a number of linear furanoterpenes containing 21 and 25 carbon atoms have also been obtained (see pages 23 and 28). 

Another important group of sesterterpenes with a tetracarbocyclic skeleton has been found in sponges of the genus Cacospongia, and in the taxonomically related Spongia officinalis. Their structures are shown in Chart 11. 

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