Spiny projection neuron medium-sized

The NAc is the major component of the ventral striatum, and of the so-called limbic striatum. This striatal region corresponds to the entire anterior and ventromedial sector of the striatum and continues anteriorly into the NAc and the olfactory tubercle (Heimer and Wilson, 1975 Nauta, 1989). In the NAc, the principal neurons, which are the medium spiny projection neurons, make up approximately 90% of the total neuronal population and are generally similar to those of the striatal (i.e., neostriatal) counterpart. The local circuit neurons represent approximately 10% of the NAc neurons and vary greatly in size,... 

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