Spermidine derivative, antifouling

The antifouling sponge metabolite pseudoceratidine (1245) was characterized from the Japanese Pseudoceratina purpurea (1253). This spermidine derivative has excellent larval settlement and metamorphosis inhibitory activity against the barnacle Balanus amphitrite (ED50 = 8.0 pig cm-3), and is the first example of an antifouling spermidine derivative. The four tauroacidins A (1246/1247) and B (1248/1249), with tyrosine kinase inhibitory activity, were isolated from the... [Pg.185]

Tsukamoto S, Kato H, Hirota H, Fusetani N (1996) Pseudoceratidine A New Antifouling Spermidine Derivative from the Marine Sponge Pseudoceratina purpurea. Tetrahedron Lett 37 1439... [Pg.437]

Tsukamoto, S., Kato, H., Hirota, H., and Fusetani, N., Pseudoceratidine a new antifouling spermidine derivative from the marine sponge Pseudoceratina purpurea, Tetrahedron Lett., 37, 1439, 1996. [Pg.566]

A spermidine derivative with two 4,5-dibromopyrrole-2-carbamyl units, pseudo-ceratidine (120), has been isolated from the sponge Pseudoceratina purpurea as an antifouling compound [145]. [Pg.293]

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