Spectroscopy in vivo

V. H. W. Mak, R. O. Potts, and R. H. Guy. Oleic acid concentration and effect in human stratum corneum Non-invasive determination by attenuated total reflectance infrared spectroscopy in vivo. J. Control. Release 12 67-75 (1990). 

Bottomley PA (1987) Spatial localization in NMR spectroscopy in vivo. Ann NY Acad Sci 508 333-348 Bottomley PA, Edelstein WA, Foster TH, Adams WA (1985) In vivo solvent-suppressed localized hydrogen nuclear magnetic resonance spectroscopy a window to metabolism Proc Natl Acad Sci USA 82 2148-2152 Brown TR, Kincaid BM, Ugurbil K (1982) NMR chemical shift imaging in three dimensions. Proc Natl Acad Sci USA 79 3523-3526... 

H. Hofeler, D. Jensen, M. M. Pike, J. L. Delayre, V. P. Cirillo, C. S. Springer, Jr, E. T. Fossel and J. A. Balschi (1987). Sodium transport and phosphorus metabolism in sodium-loaded yeast simultaneous observation with sodium-23 and phosphorus-31 NMR spectroscopy in vivo. Biochemistry, 26, 4953-4962. 

Bottomley PA (1987) Spatial localization in NMR spectroscopy in vivo. Annal NY Acad Sci 508 333-348 Brown H, Prescott R (1999) Applied mixed models in medicine. Wiley, Chichester... 

It has been claimed by some workers that Li is more readily transported into erythrocytes than is Li and that there are differences in their biological effects (72). It has also been postulated that Li may produce fewer side effects or less toxicity than the naturally occurring isotope mixture (73). Li nuclear magnetic resonance (NMR) spectroscopy in vivo has been used to measure tissue lithium levels in humans noninvasively and with safety. These experiments showed tissue lithium concentrations significantly lower than those in the serum (74). The NMR technique has been used also to distinguish the isotopes in transport studies in red blood cells (75, 76) and in other cell types (77). 

Figure 18. Example of diffuse reflectance spectroscopy in vivo. The reflectance spectrum from normal skin/muscle was measured in an animal model following intravenous administration of a non-fluorescent photosensitizer. The spectra show monomeric and aggregated drug and the changes in these components with time after injection.

D. Z. Balia and C. Faber, Localized Intermolecular Zero-Quantum Coherence Spectroscopy in vivo . Concepts Magn. Reson., A, 2008, 32A, 117. 

Woodruff, W, H., Spiro, T. G. and Gilvarg, C. (1974) Raman spectroscopy in vivo evidence on the structure of dipicolinate in intact spores of Bacillus megaterium. Biochem. Biophys. Res. Common. 58, 197-203. 

Our analysis was focused in the Qg parameter because of its relation with cervical abnormalities detected by electrical impedance spectroscopy in-vivo [15]. 

See also Chemical Shift and Relaxation Reagents in NMR Diffusion Studied Using NMR Spectroscopy In Vivo NMR, Methods In Vivo NMR, Applications -In Vivo NMR, Applications, Other Nuclei MRI Applications, Clinical MRI Applications, Clinical Flow Studies MRI Instrumentation MRI Theory NMR Microscopy NMR Relaxation Rates. 

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