Spectroscopy disadvantages

Atomic absorption spectroscopy, disadvantages in HPLC, 142 Aztreonam... 

Each type of mass spectrometer has its associated advantages and disadvantages. Quadrupole-based systems offer a fairly simple ion optics design that provides a certain degree of flexibility with respect to instrument configuration. For example, quadrupole mass filters are often found in hybrid systems, that is, coupled with another surface analytical method, such as electron spectroscopy for chemical analysis or scanning Auger spectroscopy. 

The most widely used techniques for surface analysis are Auger electron spectroscopy (AES), x-ray photoelectron spectroscopy (XPS), secondary ion mass spectroscopy (SIMS), Raman and infrared spectroscopy, and contact angle measurement. Some of these techniques have the ability to determine the composition of the outermost atomic layers, although each technique possesses its own special advantages and disadvantages. 

The physical methods mostly require ultra high vacuum conditions having the disadvantage of not being applicable directly to solvent swollen films, but recent developments of in situ measurements in SIMS X-ray diffraction surface enhanced Raman spectroscopy (SERS) and scanning electrochemical tunneling microscopy... 

Photofragment spectroscopy is extremely sensitive, but it has the disadvantage that one is only sensitive to absorption that leads to photodissociation. For single-photon experiments, this means that one is restricted... 

Raman spectroscopy is well suited for food analysis because the high water content of food that is a disadvantage for IR spectroscopy does not disturb Raman spectroscopy. 

The main advantages and disadvantages of transmission and photoacoustic spectroscopies are summarized in Table I. The advantages... 

We shall concern ourselves here with the use of an X-ray probe as a surface analysis technique in X-ray photoelectron spectroscopy (XPS) also known as Electron Spectroscopy for Chemical Analysis (ESCA). High energy photons constitute the XPS probe, which are less damaging than an electron probe, therefore XPS is the favoured technique for the analysis of the surface chemistry of radiation sensitive materials. The X-ray probe has the disadvantage that, unlike an electron beam, it cannot be focussed to permit high spatial resolution imaging of the surface. 

IV. Advantages and Disadvantages of Using Fluorescence Correlation Spectroscopy to Study Protein Conformational Changes... 

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